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| Cat.No | ACP13931 | Target Name | TRIM58 |
|---|---|---|---|
| Target Synonyms | BIA2; DKFZp434C091; Protein BIA2; TRI58_HUMAN; Trim58; Tripartite motif-containing protein 58 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-486 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NG06 |
|---|
Uniprot Id
Q8NG06
Target Species
Human
Target Name
TRIM58
Target Full Name
E3 ubiquitin-protein ligase TRIM58
Target Function
E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.
Target Protein Families
TRIM/RBCC family
Target Tissue Specificity
Expressed in erythroblasts.
Target Synonyms
BIA2; DKFZp434C091; Protein BIA2; TRI58_HUMAN; Trim58; Tripartite motif-containing protein 58
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