Recombinant Human Serine/threonine-protein kinase Nek1 (NEK1), Truncated

Cat.No	ACP14343	Target Name	NEK1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP14343

Target Name

NEK1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q96PY6

Background Information

Uniprot Id

Q96PY6
Target Species

Human
Target Name

NEK1
Target Full Name

Serine/threonine-protein kinase Nek1
Target Function

Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Involved in DNA damage checkpoint control and for proper DNA damage repair. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death. May be implicated in the control of meiosis. Involved in cilium assembly.
Target Involvement

Short-rib thoracic dysplasia 6 with or without polydactyly (SRTD6)
Target Subcellular Location

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm.
Target Protein Families

Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily
Target Tissue Specificity

High fetal expression in the brain and kidney.
Target Synonyms

DKFZp686D06121; DKFZp686K12169; kat; KIAA1901; MGC138800; MGC189817; NEK1; NEK1_HUMAN; Never in mitosis A-related kinase 1; Never in mitosis gene A-related kinase 1; NIMA (never in mitosis gene a)-related kinase 1; NIMA-related kinase 1; NimA-related protein kinase 1; NY-REN-55; OTTHUMP00000219432; OTTHUMP00000219433; OTTHUMP00000219434; OTTHUMP00000219435; Protein-serine/threonine kinase; Renal carcinoma antigen NY-REN-55; Serine/threonine-protein kinase Nek1; SRPS2; SRPS2A; SRTD6
Target Background

The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.

Recombinant Human Serine/threonine-protein kinase Nek1 (NEK1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Serine/threonine-protein kinase Nek1 (NEK1), Truncated Now

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