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| Cat.No | ACP14734 | Target Name | MARC2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 36-335 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q969Z3 |
|---|
Uniprot Id
Q969Z3
Target Species
Human
Target Name
MTARC2
Target Full Name
Mitochondrial amidoxime reducing component 2
Target Function
Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction
Target Subcellular Location
Mitochondrion outer membrane; Peripheral membrane protein. Peroxisome.
Target Synonyms
FLJ20605; MARC2; Mitochondrial amidoxime reducing component 2; mitochondrial; Moco sulfurase C terminal domain containing protein 2; MOCO sulphurase C-terminal domain containing 2; Molybdenum cofactor sulfurase C terminal domain containing protein 2; MOSC domain containing protein 2 mitochondrial; MOSC domain-containing protein 2; MOSC2; MOSC2_HUMAN; RP11-270A6.1
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