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| Cat.No | ACP14826 | Target Name | GRPEL2 |
|---|---|---|---|
| Target Synonyms | GrpE like 2; mitochondrial; GrpE protein homolog 2; GRPE2_HUMAN; GRPEL 2; Grpel2; mitochondrial; Mt GrpE#2; Mt-GrpE#2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 33-225 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TAA5 |
|---|
Uniprot Id
Q8TAA5
Target Species
Human
Target Name
GRPEL2
Target Full Name
GrpE protein homolog 2, mitochondrial
Target Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
GrpE family
Target Synonyms
GrpE like 2; mitochondrial; GrpE protein homolog 2; GRPE2_HUMAN; GRPEL 2; Grpel2; mitochondrial; Mt GrpE#2; Mt-GrpE#2
Target Background
Predicted to enable adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion.
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