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| Cat.No | ACP16762 | Target Name | CEP162 |
|---|---|---|---|
| Target Synonyms | C6orf84; Kiaa1009; Protein QN1 homolog; QN1_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5TB80 |
|---|
Uniprot Id
Q5TB80
Target Species
Human
Target Name
CEP162
Target Full Name
Centrosomal protein of 162 kDa
Target Function
Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base. Required to mediate CEP290 association with microtubules.
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. Nucleus. Note=Localizes to the distal end of centrioles throughout the cell cycle. During ciliogenesis, found at the cilia base. Localizes to spindle microtubules during mitosis.
Target Protein Families
CEP162 family
Target Synonyms
C6orf84; Kiaa1009; Protein QN1 homolog; QN1_HUMAN
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