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Recombinant Human Latent-transforming growth factor beta-binding protein 1 (LTBP1), Truncated

ACP17733

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Specifications

Cat.No	ACP17733	Target Name	Ltbp1
Target Synonyms	9430031G15Rik; 9830146M04; Latent transforming growth factor beta binding protein 1; Latent-transforming growth factor beta-binding protein 1; Latent-transforming growth factor beta-binding protein, isoform 1L; Latent-transforming growth factor beta-binding protein, isoform 1S; LBT1S; LTBP-1; Ltbp1; LTBP1_HUMAN; MGC163161; TGF-beta1-BP-1; Tgfb; Transforming growth factor beta-1-binding protein 1; Transforming growth factor beta-1-masking protein large subunit	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q14766

Background Information

Uniprot Id

Q14766
Target Species

Human
Target Name

LTBP1
Target Full Name

Latent-transforming growth factor beta-binding protein 1
Target Function

Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.
Target Subcellular Location

Secreted. Secreted, extracellular space, extracellular matrix.
Target Protein Families

LTBP family
Target Tissue Specificity

Expressed in the aorta (at protein level). Isoform Long: Expressed in fibroblasts.
Target Synonyms

9430031G15Rik; 9830146M04; Latent transforming growth factor beta binding protein 1; Latent-transforming growth factor beta-binding protein 1; Latent-transforming growth factor beta-binding protein, isoform 1L; Latent-transforming growth factor beta-binding protein, isoform 1S; LBT1S; LTBP-1; Ltbp1; LTBP1_HUMAN; MGC163161; TGF-beta1-BP-1; Tgfb; Transforming growth factor beta-1-binding protein 1; Transforming growth factor beta-1-masking protein large subunit

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Recombinant Human Latent-transforming growth factor beta-binding protein 1 (LTBP1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Latent-transforming growth factor beta-binding protein 1 (LTBP1), Truncated Now

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