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Recombinant Human Periodic tryptophan protein 1 homolog (PWP1)

ACP18275

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18275 Target NamePWP1
Target SynonymsKeratinocyte protein IEF SSP 9502; Periodic tryptophan protein 1 homolog; PWP1; PWP1 homolog; PWP1_HUMANFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-501
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ13610
Background Information
  • Uniprot Id

    Q13610

  • Target Species

    Human

  • Target Name

    PWP1

  • Target Full Name

    Periodic tryptophan protein 1 homolog

  • Target Function

    Chromatin-associated factor that regulates transcription. Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription. Regulates the epigenetic status of rDNA.

  • Target Subcellular Location

    Nucleus. Nucleus, nucleolus. Chromosome.

  • Target Protein Families

    WD repeat PWP1 family

  • Target Tissue Specificity

    High levels seen in the placenta, skeletal muscle, kidney and pancreas while lower levels were seen in the heart, brain and lung.

  • Target Synonyms

    Keratinocyte protein IEF SSP 9502; Periodic tryptophan protein 1 homolog; PWP1; PWP1 homolog; PWP1_HUMAN

  • Target Background

    The protein encoded by this gene contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma. Three transcript variants encoding different isoforms have been found for this gene.

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