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| Cat.No | ACP18921 | Target Name | HEMGN |
|---|---|---|---|
| Target Synonyms | CT155; EDAG; EDAG-1; Erythroid differentiation-associated gene protein; Hemgn; HEMGN_HUMAN; Hemogen; Hemopoietic gene protein; NDR; Negative differentiation regulator protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-484 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BXL5 |
|---|
Uniprot Id
Q9BXL5
Target Species
Human
Target Name
HEMGN
Target Full Name
Hemogen
Target Function
Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various le
Target Synonyms
CT155; EDAG; EDAG-1; Erythroid differentiation-associated gene protein; Hemgn; HEMGN_HUMAN; Hemogen; Hemopoietic gene protein; NDR; Negative differentiation regulator protein
Target Background
Predicted to be involved in regulation of osteoblast differentiation. Located in nucleoplasm.
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