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Recombinant Human Synaptonemal complex protein 3 (SYCP3)

ACP19454

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Specifications

Cat.No	ACP19454	Target Name	SYCP3
Target Synonyms	choline phosphotransferase 1; chpt1; COR 1; COR1; MGC71888; RNASCP3; SCP 3; SCP-3; SCP3; SPGF4; Sycp 3; Sycp3; SYCP3_HUMAN; Synaptonemal complex protein 3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-236
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IZU3

Background Information

Uniprot Id

Q8IZU3
Target Species

Human
Target Name

SYCP3
Target Full Name

Synaptonemal complex protein 3
Target Function

Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells. Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2.
Target Involvement

Spermatogenic failure 4 (SPGF4); Pregnancy loss, recurrent, 4 (RPRGL4)
Target Subcellular Location

Nucleus. Chromosome. Chromosome, centromere.
Target Protein Families

XLR/SYCP3 family
Target Tissue Specificity

Testis-specific.
Target Synonyms

choline phosphotransferase 1; chpt1; COR 1; COR1; MGC71888; RNASCP3; SCP 3; SCP-3; SCP3; SPGF4; Sycp 3; Sycp3; SYCP3_HUMAN; Synaptonemal complex protein 3
Target Background

This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.

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Recombinant Human Synaptonemal complex protein 3 (SYCP3)

Specifications

Immunogen Information

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