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Recombinant Human Lysophosphatidylcholine acyltransferase 2 (LPCAT2), Truncated

ACP19534

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19534 Target NameLPCAT2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ7L5N7
Background Information
  • Uniprot Id

    Q7L5N7

  • Target Species

    Human

  • Target Name

    LPCAT2

  • Target Full Name

    Lysophosphatidylcholine acyltransferase 2

  • Target Function

    Exhibits both acyltransferase and acetyltransferase activities. Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Involved in the regulation of lipid droplet number and size.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Lipid droplet.

  • Target Protein Families

    1-acyl-sn-glycerol-3-phosphate acyltransferase family

  • Target Synonyms

    1 acylglycerophosphocholine O acyltransferase; 1 alkylglycerophosphocholine O acetyltransferase; 1-acylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; A330042H22; Acetyl CoA:lyso PAF acetyltransferase; Acetyl-CoA:lyso-PAF acetyltransferase; Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; acyl CoA:lysophosphatidylcholine acyltransferase 2; Acyl-CoA:lysophosphatidylcholine acyltransferase member 1; Acyltransferase like 1; Acyltransferase like 1A; Acyltransferase-like 1; AYTL1; Aytl1a; DKFZp686H22112; FLJ20481; lpafat1; LPC acyltransferase 2; LPCAT-2; LPCAT2; Lyso PAF acetyltransferase; Lyso platelet activating factor (PAF) acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT; LysoPAFAT/LPCAT2; LysoPC acyltransferase 2; Lysophosphatidylcholine acyltransferase 2; OTTMUSP00000029641; PCAT2_HUMAN; RGD1563994

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