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| Cat.No | ACP20778 | Target Name | PLRG1 |
|---|---|---|---|
| Target Synonyms | Arabidopsis, Arabidopsis); Pleiotropic regulator 1; PLRG 1; PLRG1; PLRG1_HUMAN; PRL 1; PRL1; PRL1, Cwc1; MGC110980; pleiotropic regulator 1 (PRL1 homolog, homolof of; PRP46; PRPF46; TANGO4; transport and golgi organization 4 homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-514 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43660 |
|---|
Uniprot Id
O43660
Target Species
Human
Target Name
PLRG1
Target Full Name
Pleiotropic regulator 1
Target Function
Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.
Target Subcellular Location
Nucleus. Nucleus speckle.
Target Protein Families
WD repeat PRL1/PRL2 family
Target Synonyms
Cwc1; MGC110980; pleiotropic regulator 1 (PRL1 homolog, Arabidopsis); Pleiotropic regulator 1; PLRG 1; PLRG1; PLRG1_HUMAN; PRL 1; PRL1; PRL1, Arabidopsis, homolof of; PRP46; PRPF46; TANGO4; transport and golgi organization 4 homolog
Target Background
This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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