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| Cat.No | ACP21657 | Target Name | TRIM38 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-465 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O00635 |
|---|
Uniprot Id
O00635
Target Species
Human
Target Name
TRIM38
Target Full Name
E3 ubiquitin-protein ligase TRIM38
Target Function
E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
TRIM38; RNF15; RORET; E3 ubiquitin-protein ligase TRIM38; EC 2.3.2.27; RING finger protein 15; RING-type E3 ubiquitin transferase TRIM38; Tripartite motif-containing protein 38; Zinc finger protein RoRet
Target Background
This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4.
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