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Recombinant Human Ras association domain-containing protein 10 (RASSF10)

ACP21914

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Specifications

Cat.No	ACP21914	Target Name	RASSF10
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-507	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	A6NK89

Background Information

Uniprot Id

A6NK89
Target Species

Human
Target Name

RASSF10
Target Full Name

Ras association domain-containing protein 10
Target Function

Plays an important role in regulating embryonic neurogenesis.
Target Subcellular Location

Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=During interphase, predominantly cytoplasmic, although some nuclear staining in several tumor cell contexts. During prophase, observed at developing centrosomes. Displays persistent localization with centrosomally radiating microtubule bundles until late telophase. Associates with spindle poles particularly during metaphase and anaphase before relocating back to the cytoplasm.
Target Tissue Specificity

Expressed in brain. Tends to be down-regulated in astrocytic gliomas due to promoter methylation. Methylation occurs early in gliomagenesis and the extent of methylation parallels with higher glioma grades, so that methylation is observed in close to 70%
Target Synonyms

4632411J06Rik; Ras association (RalGDS/AF 6) domain family (N terminal) member 10; Ras association (RalGDS/AF-6) domain family (N-terminal) member 10; ras association domain containing protein 10; Ras association domain-containing protein 10; RASFA_HUMAN; RASSF10

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Recombinant Human Ras association domain-containing protein 10 (RASSF10)

Specifications

Immunogen Information

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