Rabbit anti-Human ENO3 Polyclonal Antibody

Uniprot Id

P13929

Target Species

Human

Target Name

ENO3

Target Full Name

Beta-enolase

Target Function

Appears to have a function in striated muscle development and regeneration.

Target Involvement

Glycogen storage disease 13 (GSD13)

Target Subcellular Location

Cytoplasm.

Target Protein Families

Enolase family

Target Tissue Specificity

The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.

Target Research Area

Metabolism

Target Synonyms

2 phospho D glycerate hydro lyase; 2 phospho D glycerate hydrolyase; 2-phospho-D-glycerate hydro-lyase; Beta enolase; Beta-enolase; ENO3; ENOB_HUMAN; Enolase 3 (beta muscle); Enolase 3; Enolase3; GSD13; MSE; Muscle specific enolase; Muscle-specific enolase; Skeletal muscle enolase

Target Background

This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have be associated glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described.