Rabbit anti-Human INPP5A Polyclonal Antibody

The antibody against INPP5A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 10-200 of human INPP5A (NP_005530.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00481A

Number

Cat.No	ADA-00481A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	INPP5A
Target Synonyms	5PTASE; INPP5A	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse heart, Mouse lung, Rat testis	Application	ELISA, WB

Cat.No

ADA-00481A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

INPP5A

Target Synonyms

5PTASE; INPP5A

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse heart, Mouse lung, Rat testis

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 10-200 of human INPP5A (NP_005530.3).	Target Species	Human
Immunogen Sequence	TAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPS	Uniprot ID	Q14642

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 10-200 of human INPP5A (NP_005530.3).

Target Species

Human

Immunogen Sequence

TAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPS

Uniprot ID

Q14642

Background Information

Uniprot Id

Q14642
Target Species

Human
Target Name

INPP5A
Target Full Name

Inositol polyphosphate-5-phosphatase A
Target Function

Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells.
Target Subcellular Location

Cell membrane; Lipid-anchor. Cell projection, dendrite.
Target Protein Families

Inositol 1,4,5-trisphosphate 5-phosphatase type I family
Target Tissue Specificity

Predominantly expressed in heart, brain, and skeletal muscle. In brain; high level in Purkinje cells.
Target Research Area

Signal Transduction
Target Synonyms

4; 43 kDa inositol polyphosphate 5-phophatase; 5-trisphosphate 5-phosphatase; 5PTase; CTCL tumor antigen HD-CL-02; DKFZp434A1721; I5P1; I5P1_HUMAN; Inositol polyphosphate 5 phosphatase; inositol polyphosphate-5-phosphatase A; inositol trisphosphate-5-phosphatase; INPP5A; INPP5A inositol polyphosphate-5-phosphatase; InsP3 5-phosphatase; MGC116947; MGC116949; Type I inositol-1; type I inositol-1,4,5-trisphosphate 5-phophatase
Target Background

The protein encoded by this gene is a membrane-associated type I inositol 1, 4, 5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1, 4, 5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

Rabbit anti-Human INPP5A Polyclonal Antibody

Specifications

Immunogen Information

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