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The antibody against ENPP6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 91-440 of human ENPP6 (NP_699174.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ENPP6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 91-440 of human ENPP6 (NP_699174.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02288A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ENPP6 |
| Target Synonyms | NPP6; ENPP6 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 91-440 of human ENPP6 (NP_699174.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6UWR7 | Immunogen Sequence |
Uniprot Id
Q6UWR7
Target Species
Human
Target Name
ENPP6
Target Full Name
Glycerophosphocholine cholinephosphodiesterase ENPP6
Target Function
Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor. Note=A small amount of the protein may be found in the extracellular milieu.
Target Protein Families
Nucleotide pyrophosphatase/phosphodiesterase family
Target Tissue Specificity
Predominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level).
Target Synonyms
ENPP6; UNQ1889/PRO4334Glycerophosphocholine cholinephosphodiesterase ENPP6; GPC-Cpde; EC 3.1.4.-; EC 3.1.4.38; Choline-specific glycerophosphodiester phosphodiesterase; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; E-NPP 6; NPP-6
Target Background
Enables glycerophosphocholine cholinephosphodiesterase activity. Involved in choline metabolic process and lipid metabolic process. Located in extracellular region and plasma membrane.
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