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The antibody against GLUD2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 319-558 of human GLUD2 (NP_036216.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against GLUD2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 319-558 of human GLUD2 (NP_036216.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-02933A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GLUD2 |
| Target Synonyms | GDH2; GLUDP1; GLUD2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-431, HepG2, U-937 | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 319-558 of human GLUD2 (NP_036216.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P49448 | Immunogen Sequence |
Uniprot Id
P49448
Target Species
Human
Target Name
GLUD2
Target Full Name
Glutamate dehydrogenase 2, mitochondrial
Target Function
Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Glu/Leu/Phe/Val dehydrogenases family
Target Tissue Specificity
Expressed in retina, testis and, at a lower level, brain.
Target Synonyms
DHE4_HUMAN; GDH 2; GDH; GDH2; GLUD2; GLUDP1; Glutamate dehydrogenase 2; Glutamate dehydrogenase 2 mitochondrial; Glutamate dehydrogenase pseudogene 1; mitochondrial
Target Background
The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.
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