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The antibody against CA14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 16-290 of human CA14 (NP_036245.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CA14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 16-290 of human CA14 (NP_036245.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03928A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CA14 |
| Target Synonyms | CAXiV; CA14 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A375, Jurkat, M21, Mouse lung, U-937 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 16-290 of human CA14 (NP_036245.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9ULX7 | Immunogen Sequence |
Uniprot Id
Q9ULX7
Target Species
Human
Target Name
CA14
Target Full Name
Carbonic anhydrase 14
Target Function
Reversible hydration of carbon dioxide.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Alpha-carbonic anhydrase family
Target Tissue Specificity
High expression in all parts of the central nervous system and lower expression in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle.
Target Synonyms
CA 14; CA XIV; CA-XIV; CA14; CAH14_HUMAN; Carbonate dehydratase XIV; Carbonic anhydrase 14; Carbonic anhydrase XIV; Carbonic dehydratase; CAXIV; UNQ690/PRO1335
Target Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.
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