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Rabbit anti-Human HOXD3 Polyclonal Antibody

The antibody against HOXD3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 263-432 of human HOXD3 (NP_008829.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05168A

The antibody against HOXD3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 263-432 of human HOXD3 (NP_008829.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-05168A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHOXD3
Target SynonymsHOX4; HOX1D; HOX4A; Hox-4.1; HOXD3FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesU-251MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 263-432 of human HOXD3 (NP_008829.3).Target SpeciesHuman
Immunogen SequenceASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGGNFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQGRLPEAPKLTHLUniprot IDP31249
Background Information
  • Uniprot Id

    P31249

  • Target Species

    Human

  • Target Name

    HOXD3

  • Target Full Name

    Homeobox protein Hox-D3

  • Target Function

    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Antp homeobox family

  • Target Synonyms

    Homeo box D3 ; Homeobox D3; Homeobox protein Hox D3; Homeobox protein Hox-4A; Homeobox protein Hox-D3; Homeobox protein HoxD3; Homeodomain protein; HOX 1D; HOX 4; Hox 4.1; Hox 4A; HOX D3; Hox-4.1 mouse homolog of ; HOX1D; HOX4; Hox4.1; HOX4A; HOXD 3; HOXD3; HXD3_HUMAN; MGC10470

  • Target Background

    This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes.

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