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The antibody against DDI1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 97-396 of human DDI1 (NP_001001711.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DDI1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 97-396 of human DDI1 (NP_001001711.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05620A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DDI1 |
| Target Synonyms | DDI1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 97-396 of human DDI1 (NP_001001711.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8WTU0 | Immunogen Sequence |
Uniprot Id
Q8WTU0
Target Species
Human
Target Name
DDI1
Target Full Name
Protein DDI1 homolog 1
Target Function
Probable aspartic protease (Probable). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 (Probable). Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity.
Target Protein Families
DDI1 family
Target Synonyms
DDI1Protein DDI1 homolog 1; EC 3.4.23.-
Target Background
Predicted to enable aspartic-type endopeptidase activity. Involved in several processes, including cellular response to hydroxyurea; proteasomal protein catabolic process; and regulation of DNA stability.
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