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The antibody against YPEL5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human YPEL5 (NP_057145.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against YPEL5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human YPEL5 (NP_057145.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05710A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | YPEL5 |
| Target Synonyms | CGI-127; YPEL5 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, HT-29, Mouse brain, Mouse lung, Mouse testis, Rat lung, Rat testis, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human YPEL5 (NP_057145.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MGRIFLDHIGGTRLFSCANCDTILTNRSELISTRFTGATGRAFLFNKVVNLQYSEVQDRVMLTGRHMVRDVSCKNCNSKLGWIYEFATEDSQRYKEGRVILERALVRESEGFEEHVPSDNS | Uniprot ID | P62699 |
Uniprot Id
P62699
Target Species
Human
Target Name
YPEL5
Target Full Name
Protein yippee-like 5
Target Function
Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Required for normal cell proliferation.
Target Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody.
Target Protein Families
Yippee family
Target Synonyms
YPEL5; CGI-127Protein yippee-like 5
Target Background
Predicted to enable metal ion binding activity. Predicted to be involved in cell population proliferation. Part of ubiquitin ligase complex.
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