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Rabbit anti-Human FLRT2 Polyclonal Antibody

The antibody against FLRT2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07024A

The antibody against FLRT2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-07024A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFLRT2
Target SynonymsFLRT2FormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1).Target SpeciesHuman
Immunogen SequenceSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTPUniprot IDO43155
Background Information
  • Uniprot Id

    O43155

  • Target Species

    Human

  • Target Name

    FLRT2

  • Target Full Name

    Leucine-rich repeat transmembrane protein FLRT2

  • Target Function

    Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis

  • Target Subcellular Location

    Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane. Cell junction, focal adhesion. Secreted, extracellular space, extracellular matrix. Microsome membrane. Secreted. Cell junction, synapse, synaptosome.

  • Target Tissue Specificity

    Expressed in pancreas, skeletal muscle, brain, and heart.

  • Target Synonyms

    FLRT2; KIAA0405; UNQ232/PRO265; Leucine-rich repeat transmembrane protein FLRT2; Fibronectin-like domain-containing leucine-rich transmembrane protein 2

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