Rabbit anti-Human CPSF2 Polyclonal Antibody

The antibody against CPSF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 450-700 of human CPSF2 (NP_059133.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08926A

Number

Cat.No	ADA-08926A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CPSF2
Target Synonyms	CPSF100; CPSF2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, Mouse kidney, LO2, Mouse liver, Raji, U-251MG, U-937	Application	ELISA, WB

Cat.No

ADA-08926A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CPSF2

Target Synonyms

CPSF100; CPSF2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, Mouse kidney, LO2, Mouse liver, Raji, U-251MG, U-937

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 450-700 of human CPSF2 (NP_059133.1).	Target Species	Human
Uniprot ID	Q9P2I0	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 450-700 of human CPSF2 (NP_059133.1).

Target Species

Human

Uniprot ID

Q9P2I0

Immunogen Sequence

Background Information

Uniprot Id

Q9P2I0
Target Species

Human
Target Name

CPSF2
Target Full Name

Cleavage and polyadenylation specificity factor subunit 2
Target Function

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.
Target Subcellular Location

Nucleus.
Target Protein Families

Metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily
Target Synonyms

Cleavage and polyadenylation specific factor 2; cleavage and polyadenylation specific factor 2; 100kDa; Cleavage and polyadenylation specificity factor 100 kDa subunit; Cleavage and polyadenylation specificity factor subunit 2; CPSF 100 kDa subunit; CPSF 2; CPSF100; Cpsf2; CPSF2_HUMAN; KIAA1367; zgc:92484
Target Background

Predicted to enable RNA binding activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Located in membrane. Part of mRNA cleavage and polyadenylation specificity factor complex.

Rabbit anti-Human CPSF2 Polyclonal Antibody

Specifications

Immunogen Information

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