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The antibody against SLCO1A2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 400-500 of human SLCO1A2 (NP_066580.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SLCO1A2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 400-500 of human SLCO1A2 (NP_066580.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-08998A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLCO1A2 |
| Target Synonyms | OATP; OATP-A; OATP1A2; SLC21A3; SLCO1A2 | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat liver | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human SLCO1A2 (NP_066580.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | SYEGIPQDLYVENDIFADC | Uniprot ID | P46721 |
Uniprot Id
P46721
Target Species
Human
Target Name
SLCO1A2
Target Full Name
Solute carrier organic anion transporter family member 1A2
Target Function
Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids. Selectively inhibited by the grapefruit juice component naringin.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Organo anion transporter (TC 2.A.60) family
Target Synonyms
OATP; OATP-1; OATP-A; OATP1A2; Organic anion-transporting polypeptide 1; SLC21A3; SLCO1A2; SO1A2_HUMAN; Sodium-independent organic anion transporter; Solute carrier family 21 member 3; Solute carrier organic anion transporter family member 1A2
Target Background
This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants.
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