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Rabbit anti-Human ELF2 Polyclonal Antibody

The antibody against ELF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ELF2 (NP_006865.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09318A

The antibody against ELF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ELF2 (NP_006865.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09318A ClonalityPolyclonal
Host SpeciesRabbitTarget NameELF2
Target SynonymsEU32; NERF; NERF-2; NERF-1A; NERF-1B; NERF-1a; b; ELF2FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesA-549, HL-60, Jurkat, MCF7ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ELF2 (NP_006865.1).Target SpeciesHuman
Immunogen SequenceMATSLHEGPTNQLDLLIRAVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCVSTPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKVGRKPKTQQSPISNGSPELGIKKKPUniprot IDQ15723
Background Information
  • Uniprot Id

    Q15723

  • Target Species

    Human

  • Target Name

    ELF2

  • Target Full Name

    ETS-related transcription factor Elf-2

  • Target Function

    Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.; Isoform 2 may function in repression of RUNX1-mediated transactivation.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ETS family

  • Target Tissue Specificity

    Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung,

  • Target Synonyms

    ELF2; NERFETS-related transcription factor Elf-2; E74-like factor 2; New ETS-related factor

  • Target Background

    Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Located in cytosol and nuclear body.

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