Rabbit anti-Human CBR3 Polyclonal Antibody

The antibody against CBR3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 118-277 of human CBR3 (NP_001227.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11026A

Number

Cat.No	ADA-11026A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CBR3
Target Synonyms	hCBR3; SDR21C2; HEL-S-25; CBR3	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, BT-474, MCF7, Mouse brain, Mouse lung, Mouse ovary, NCI-H460, SW480	Application	ELISA, WB

Cat.No

ADA-11026A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CBR3

Target Synonyms

hCBR3; SDR21C2; HEL-S-25; CBR3

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, BT-474, MCF7, Mouse brain, Mouse lung, Mouse ovary, NCI-H460, SW480

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 118-277 of human CBR3 (NP_001227.1).	Target Species	Human
Immunogen Sequence	TRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW	Uniprot ID	O75828

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 118-277 of human CBR3 (NP_001227.1).

Target Species

Human

Immunogen Sequence

TRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW

Uniprot ID

O75828

Background Information

Uniprot Id

O75828
Target Species

Human
Target Name

CBR3
Target Full Name

Carbonyl reductase [NADPH] 3
Target Function

Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).
Target Subcellular Location

Cytoplasm.
Target Protein Families

Short-chain dehydrogenases/reductases (SDR) family
Target Tissue Specificity

Detected in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis.
Target Synonyms

Carbonyl reductase (NADPH) 3; Carbonyl reductase (NADPH) 3 EC 1.1.1.184; Carbonyl reductase [NADPH] 3; Carbonyl reductase 3; CBR 3; CBR3; CBR3_HUMAN; EC 1.1.1.184; Epididymis secretory protein Li 25; hCBR3; HEL S 25; NADPH dependent carbonyl reductase 3; NADPH-dependent carbonyl reductase 3; SDR21C2; Short chain dehydrogenase/reductase family 21C member 2
Target Background

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

Rabbit anti-Human CBR3 Polyclonal Antibody

Specifications

Immunogen Information

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