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| Cat.No | ACP11688 | Target Name | CXXC1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-656 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P0U4 |
|---|
Uniprot Id
Q9P0U4
Target Species
Human
Target Name
CXXC1
Target Full Name
CXXC-type zinc finger protein 1
Target Function
Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.
Target Subcellular Location
Nucleus speckle. Nucleus. Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
2410002I16Rik; 5830420C16Rik; AI426635; CFP 1; CFP1; CpG binding protein ; CpG-binding protein; CXXC 1; CXXC finger 1; CXXC finger 1 PHD domain; CXXC finger protein 1; CXXC type zinc finger protein 1; CXXC-type zinc finger protein 1; CXXC1; CXXC1_HUMAN; DNA binding protein with PHD finger and CXXC domain ; hCGBP; HsT2645; PCCX 1; PCCX1; PHD finger and CXXC domain containing protein 1; PHD finger and CXXC domain-containing protein 1; PHF 18; PHF18; Protein containing CXXC domain 1; SPP 1; SPP1; ZCGPC 1; ZCGPC1; Zinc finger; CpG binding type containing 1
Target Background
This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development.
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