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The antibody against ACOT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 222-483 of human ACOT2 (NP_006812.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against ACOT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 222-483 of human ACOT2 (NP_006812.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-05671A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ACOT2 |
| Target Synonyms | MTE1; PTE2; CTE1A; PTE2A; CTE-IA; ZAP128; ACOT2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, 293T, LO2, U-87MG | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 222-483 of human ACOT2 (NP_006812.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P49753 | Immunogen Sequence |
Uniprot Id
P49753
Target Species
Human
Target Name
ACOT2
Target Full Name
Acyl-coenzyme A thioesterase 2, mitochondrial
Target Function
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays higher activity toward long chain acyl CoAs (C14-C20). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria.
Target Subcellular Location
Mitochondrion.
Target Protein Families
C/M/P thioester hydrolase family
Target Tissue Specificity
Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas.
Target Synonyms
ACOT2; PTE2; PTE2AAcyl-coenzyme A thioesterase 2; mitochondrial; Acyl-CoA thioesterase 2; EC 3.1.2.2; Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128
Target Background
This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants.
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