Rabbit anti-Human ADRA2B Polyclonal Antibody

The antibody against ADRA2B was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human ADRA2B (NP_000673.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08971A

Number

Cat.No	ADA-08971A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ADRA2B
Target Synonyms	FAME2; ADRA2L1; ADRARL1; ADRA2RL1; ALPHA2BAR; alpha-2BAR; ADRA2B	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, Mouse skeletal muscle, Rat kidney, Rat liver, U-87MG	Application	ELISA, WB

Cat.No

ADA-08971A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ADRA2B

Target Synonyms

FAME2; ADRA2L1; ADRARL1; ADRA2RL1; ALPHA2BAR; alpha-2BAR; ADRA2B

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, Mouse skeletal muscle, Rat kidney, Rat liver, U-87MG

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ADRA2B (NP_000673.2).	Target Species	Human
Immunogen Sequence	MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSI	Uniprot ID	P18089

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ADRA2B (NP_000673.2).

Target Species

Human

Immunogen Sequence

MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSI

Uniprot ID

P18089

Background Information

Uniprot Id

P18089
Target Species

Human
Target Name

ADRA2B
Target Full Name

Alpha-2B adrenergic receptor
Target Function

Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
Target Involvement

Epilepsy, familial adult myoclonic, 2 (FAME2)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA2B sub-subfamily
Target Synonyms

ADRA2B; ADRA2L1; ADRA2RL1; Alpha-2B adrenergic receptor; Alpha-2 adrenergic receptor subtype C2; Alpha-2B adrenoreceptor; Alpha-2B adrenoceptor; Alpha-2BAR
Target Background

This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system.

Rabbit anti-Human ADRA2B Polyclonal Antibody

Specifications

Immunogen Information

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