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The antibody against AGXT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 183-392 of human AGXT (NP_000021.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against AGXT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 183-392 of human AGXT (NP_000021.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05928A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AGXT |
| Target Synonyms | AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1; Ser-PyrAT; AGXT | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat skeletal muscle | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 183-392 of human AGXT (NP_000021.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P21549 | Immunogen Sequence |
Uniprot Id
P21549
Target Species
Human
Target Name
AGXT
Target Full Name
Alanine--glyoxylate aminotransferase
Target Involvement
Hyperoxaluria primary 1 (HP1)
Target Subcellular Location
Peroxisome. Mitochondrion.
Target Protein Families
Class-V pyridoxal-phosphate-dependent aminotransferase family
Target Tissue Specificity
Liver.
Target Research Area
Signal Transduction, Metabolism
Target Synonyms
AGT; AGT1; Agxt; AGXT1; Alanine glyoxylate aminotransferase; Alanine glyoxylate aminotransferase3; Alanine--glyoxylate aminotransferase; EC 2.6.1.44; EC 2.6.1.51; Hepatic peroxisomal alanine glyoxylate aminotransferase; Hepatic peroxisomal alanine:glyoxylate aminotransferase; L alanine glyoxylate aminotransferase 1; MS773; PH1; Serine pyruvate aminotransferase; Serine--pyruvate aminotransferase; Serine--pyruvate aminotransferase, mitochondrial; Serine:pyruvate aminotransferase; SPAT; SPT; SPYA_HUMAN; TLH6
Target Background
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.
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