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The antibody against AK7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human AK7 (NP_689540.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against AK7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human AK7 (NP_689540.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-10193A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AK7 |
| Target Synonyms | AK 7; FAP75; CFAP75; SPGF27; AK7 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, HT-29, Mouse small intestine, Mouse testis, Rat testis | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human AK7 (NP_689540.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MAEEEETAALTEKVIRTQRVFINLLDSYSSGNIGKFLSNCVVGASLEEITEEEEEEDENKSAMLEASSTKVKEGTFQIVGTLSKPDSPRPDFAVETYSAISREDLLMRLLECDVIIYNITESSQQMEEAIWAVSALSEEVSHFEKRKLFILLSTVMTWARSKALDPEDSEVPFTEEDYRRRKSHPNFLDHINAEKMVLKF | Uniprot ID | Q96M32 |
Uniprot Id
Q96M32
Target Species
Human
Target Name
AK7
Target Full Name
Adenylate kinase 7
Target Function
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.
Target Subcellular Location
Cytoplasm, cytosol. Cell projection, cilium, flagellum.
Target Protein Families
Adenylate kinase family; Dpy-30 family
Target Tissue Specificity
Expressed in sperm and airway epithelial cells (at protein level).
Target Research Area
Metabolism
Target Synonyms
AK7; Adenylate kinase 7; AK 7; EC 2.7.4.3; EC 2.7.4.6; ATP-AMP transphosphorylase 7
Target Background
This gene encodes a member of the adenylate kinase family of enzymes. The encoded enzyme is a phosphotransferase that catalyzes the reversible phosphorylation of adenine nucleotides. This enzyme plays a role in energy homeostasis of the cell. Alternative splicing results in multiple transcript variants. Mutations in the mouse gene are associated with primary ciliary dyskinesia.
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