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The antibody against BCMO1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 268-547 of human BCMO1 (NP_059125.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against BCMO1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 268-547 of human BCMO1 (NP_059125.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10047A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BCMO1 |
| Target Synonyms | BCO; BCDO; BCMO; BCDO1; BCMO1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, HT-29, LO2, Mouse liver, Mouse testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 268-547 of human BCMO1 (NP_059125.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9HAY6 | Immunogen Sequence |
Uniprot Id
Q9HAY6
Target Species
Human
Target Name
BCO1
Target Full Name
Beta,beta-carotene 15,15'-dioxygenase
Target Function
Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism.
Target Involvement
Hypercarotenemia and vitamin A deficiency, autosomal dominant (ADHVAD)
Target Protein Families
Carotenoid oxygenase family
Target Tissue Specificity
Highly expressed in retinal pigment epithelium. Also expressed in kidney, testis, liver, brain, small intestine and colon.
Target Synonyms
BCDO; BCDO1; BCDO1_HUMAN; BCMO; Bcmo1; BCO; BCO1; Beta,beta-carotene 15,15'-monooxygenase; beta-carotene 15,15'-monooxygenase 1; Beta-carotene dioxygenase 1; FLJ10730
Target Background
Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta, beta-carotene into two retinal molecules.
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