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The antibody against CD2BP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CD2BP2 (NP_006101.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CD2BP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CD2BP2 (NP_006101.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-13674A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CD2BP2 |
| Target Synonyms | LIN1; Snu40; FWP010; U5-52K; PPP1R59; P2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CD2BP2 (NP_006101.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O95400 | Immunogen Sequence |
Uniprot Id
O95400
Target Species
Human
Target Name
CD2BP2
Target Full Name
CD2 antigen cytoplasmic tail-binding protein 2
Target Function
Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Predominantly nuclear.
Target Synonyms
CD2 (cytoplasmic tail) binding protein 2 ; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2; CD2B2_HUMAN; Cd2bp2; FWP010; LIN1; Snu40; U5 snRNP 52K protein; U5-52K
Target Background
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
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