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The antibody against CDHR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human CDHR1 (NP_001165442.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CDHR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human CDHR1 (NP_001165442.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07119A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CDHR1 |
| Target Synonyms | RP65; PRCAD; CORD15; PCDH21; CDHR1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain, Mouse thymus, Rat thymus, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human CDHR1 (NP_001165442.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96JP9 | Immunogen Sequence |
Uniprot Id
Q96JP9
Target Species
Human
Target Name
CDHR1
Target Full Name
Cadherin-related family member 1
Target Function
Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells.
Target Involvement
Cone-rod dystrophy 15 (CORD15)
Target Subcellular Location
Cell membrane; Single-pass membrane protein.
Target Synonyms
Cadherin-related family member 1; CDHR1; CDHR1_HUMAN; CORD15; DKFZp434A132; KIAA1775; MT protocadherin; PCDH 21; PCDH21; PCDH21 protein; Photoreceptor cadherin; prCAD; Protocadherin-21; RP65
Target Background
This gene belongs to the cadherin superfamily of calcium-dependent cell adhesion molecules. The encoded protein is a photoreceptor-specific cadherin that plays a role in outer segment disc morphogenesis. Mutations in this gene are associated with inherited retinal dystrophies. Alternatively spliced transcript variants encoding different isoforms have been identified.
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