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The antibody against CHAD was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human CHAD (NP_001258.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CHAD was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human CHAD (NP_001258.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05330A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHAD |
| Target Synonyms | SLRR4A; CHAD | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | MCF7, U-251MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human CHAD (NP_001258.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O15335 | Immunogen Sequence |
Uniprot Id
O15335
Target Species
Human
Target Name
CHAD
Target Full Name
Chondroadherin
Target Function
Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation.
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Small leucine-rich proteoglycan (SLRP) family, SLRP class IV subfamily
Target Tissue Specificity
Present in chondrocytes at all ages.
Target Synonyms
Cartilage leucine rich protein; Cartilage leucine-rich protein; Chad; CHAD_HUMAN; Chondroadherin; Chondroadherin proteoglycan; SLRR4A
Target Background
Chondroadherin is a cartilage matrix protein thought to mediate adhesion of isolated chondrocytes. The protein contains 11 leucine-rich repeats flanked by cysteine-rich regions. The chondroadherin messenger RNA is present in chondrocytes at all ages.
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