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Rabbit anti-Human CRYGC Polyclonal Antibody

The antibody against CRYGC was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human CRYGC (NP_066269.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-01004A

The antibody against CRYGC was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human CRYGC (NP_066269.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-01004A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCRYGC
Target SynonymsCCL; CRYG3; CTRCT2; CRYGCFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMCF7, U-251MGApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-174 of human CRYGC (NP_066269.1).Target SpeciesHuman
Immunogen SequenceMGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRGEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLYUniprot IDP07315
Background Information
  • Uniprot Id

    P07315

  • Target Species

    Human

  • Target Name

    CRYGC

  • Target Full Name

    Gamma-crystallin C

  • Target Function

    Crystallins are the dominant structural components of the vertebrate eye lens.

  • Target Involvement

    Cataract 2, multiple types (CTRCT2)

  • Target Protein Families

    Beta/gamma-crystallin family

  • Target Synonyms

    CATARACT; VARIABLE ZONULAR PULVERULENT; CCL; CRGC_HUMAN; CRYG 3; Cryg 5; Cryg; CRYG3; CRYGC; Crystallin gamma 3; Crystallin gamma C; Gamma C crystallin; Gamma crystallin 2 1; Gamma crystallin 3; Gamma crystallin C; Gamma-C-crystallin; Gamma-crystallin 2-1; Gamma-crystallin 3; Gamma-crystallin C; Gammab cry; Len

  • Target Background

    This gene encodes a member of the beta/gamma-crystallin family of proteins. Crystallins constitute the major proteins of vertebrate eye lens and maintain the transparency and refractive index of the lens. This gene and several family members are present in a gene cluster on chromosome 2. Mutations in this gene have been shown to cause multiple types of cataract, including Coppock-like cataract and zonular pulverulent cataract, among others.

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