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Rabbit anti-Human DAPP1 Polyclonal Antibody

The antibody against DAPP1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-273 of human DAPP1 (NP_055210.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-06093A

The antibody against DAPP1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-273 of human DAPP1 (NP_055210.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-06093A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDAPP1
Target SynonymsBAM32; DAPP1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesRat lung, Rat spleenApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 100-273 of human DAPP1 (NP_055210.2).Target SpeciesHuman
Immunogen SequenceSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRUniprot IDQ9UN19
Background Information
  • Uniprot Id

    Q9UN19

  • Target Species

    Human

  • Target Name

    DAPP1

  • Target Full Name

    Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

  • Target Function

    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.

  • Target Subcellular Location

    Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.

  • Target Tissue Specificity

    Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.

  • Target Synonyms

    B cell adapter molecule of 32 kDa; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa; BAM32; DAPP1; DAPP1_HUMAN; DKFZp667E0716; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; Dual adaptor of phosphotyrosine and 3 phosphoinositides; hDAPP1

  • Target Background

    Enables phosphatidylinositol-3, 4, 5-trisphosphate binding activity and phosphatidylinositol-3, 4-bisphosphate binding activity. Predicted to be involved in signal transduction. Located in plasma membrane.

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