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The antibody against DAPP1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-273 of human DAPP1 (NP_055210.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against DAPP1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-273 of human DAPP1 (NP_055210.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-06093A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DAPP1 |
| Target Synonyms | BAM32; DAPP1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat lung, Rat spleen | Application | ELISA, WB, IF/ICC |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 100-273 of human DAPP1 (NP_055210.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | SSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTIR | Uniprot ID | Q9UN19 |
Uniprot Id
Q9UN19
Target Species
Human
Target Name
DAPP1
Target Full Name
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
Target Function
May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
Target Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.
Target Tissue Specificity
Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
Target Synonyms
B cell adapter molecule of 32 kDa; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa; BAM32; DAPP1; DAPP1_HUMAN; DKFZp667E0716; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; Dual adaptor of phosphotyrosine and 3 phosphoinositides; hDAPP1
Target Background
Enables phosphatidylinositol-3, 4, 5-trisphosphate binding activity and phosphatidylinositol-3, 4-bisphosphate binding activity. Predicted to be involved in signal transduction. Located in plasma membrane.
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