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The antibody against DOCK4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human DOCK4 (NP_055520.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DOCK4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human DOCK4 (NP_055520.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04853A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DOCK4 |
| Target Synonyms | DOCK4 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | DU145 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human DOCK4 (NP_055520.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8N1I0 | Immunogen Sequence |
Uniprot Id
Q8N1I0
Target Species
Human
Target Name
DOCK4
Target Full Name
Dedicator of cytokinesis protein 4
Target Function
Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration.; Has a higher guanine nucleotide exchange factor activity compared to other isoforms.
Target Subcellular Location
Cell membrane. Cell projection. Cytoplasm, cytosol.
Target Protein Families
DOCK family
Target Tissue Specificity
Widely expressed at low level. Highly expressed in skeletal muscle, prostate and ovary.; [Isoform 2]: May be specifically expressed in the brain and eye.
Target Synonyms
Dedicator of cytokinesis protein 4; Dock4; DOCK4_HUMAN; KIAA0716
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