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The antibody against EEA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1182-1411 of human EEA1 (NP_003557.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against EEA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1182-1411 of human EEA1 (NP_003557.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-06522A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EEA1 |
| Target Synonyms | MST105; ZFYVE2; MSTP105; EEA1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat brain, HT-1080, LO2, Mouse lung, U-87MG | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1182-1411 of human EEA1 (NP_003557.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q15075 | Immunogen Sequence |
Uniprot Id
Q15075
Target Species
Human
Target Name
EEA1
Target Full Name
Early endosome antigen 1
Target Function
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
Target Subcellular Location
Cytoplasm. Early endosome membrane; Peripheral membrane protein.
Target Synonyms
Early endosome antigen 1; Early endosome antigen 1; 162kD; Early endosome associated protein; EEA 1; EEA1; EEA1_HUMAN; Endosome associated protein p162; Endosome-associated protein p162; MST105; MSTP105; ZFYVE2; Zinc finger FYVE domain containing protein 2; Zinc finger FYVE domain-containing protein 2
Target Background
Enables 1-phosphatidylinositol binding activity; GTP-dependent protein binding activity; and protein homodimerization activity. Involved in endocytosis; vesicle fusion; and viral RNA genome replication. Located in cytosol and early endosome. Is extrinsic component of plasma membrane.
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