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The antibody against EG5/KIF11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 797-1056 of human EG5/EG5/KIF11 (NP_004514.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against EG5/KIF11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 797-1056 of human EG5/EG5/KIF11 (NP_004514.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-10757A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EG5/KIF11 |
| Target Synonyms | EG5; HKSP; KNSL1; MCLMR; TRIP5; EG5/KIF11 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Jurkat, SW620 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 797-1056 of human EG5/EG5/KIF11 (NP_004514.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P52732 | Immunogen Sequence |
Uniprot Id
P52732
Target Species
Human
Target Name
KIF11
Target Full Name
Kinesin-like protein KIF11
Target Function
Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface.
Target Involvement
Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation (MCLMR)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamily
Target Synonyms
EG5; HKSP; KIF11; KIF11_HUMAN; Kinesin family member 11; Kinesin like protein 1; Kinesin-like protein 1; Kinesin-like protein KIF11; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; KNSL1; MCLMR; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5; TRIP5
Target Background
This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.
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