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The antibody against FLRT2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against FLRT2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07024A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FLRT2 |
| Target Synonyms | FLRT2 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | SNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTPGLPLFTPAPSTASPTTQPPTLSIPNPSRSYTPPTP | Uniprot ID | O43155 |
Uniprot Id
O43155
Target Species
Human
Target Name
FLRT2
Target Full Name
Leucine-rich repeat transmembrane protein FLRT2
Target Function
Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis
Target Subcellular Location
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane. Cell junction, focal adhesion. Secreted, extracellular space, extracellular matrix. Microsome membrane. Secreted. Cell junction, synapse, synaptosome.
Target Tissue Specificity
Expressed in pancreas, skeletal muscle, brain, and heart.
Target Synonyms
FLRT2; KIAA0405; UNQ232/PRO265; Leucine-rich repeat transmembrane protein FLRT2; Fibronectin-like domain-containing leucine-rich transmembrane protein 2
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