Rabbit anti-Human HBG1/HBG2 Polyclonal Antibody

The antibody against HBG1/HBG2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human HBG1/HBG2 (NP_000175.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-08095A

Number

Cat.No	ADA-08095A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	HBG1/HBG2
Target Synonyms	TNCY; HBG-T1; HBG1/HBG2	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	TF-1	Application	ELISA, WB, IF/ICC

Cat.No

ADA-08095A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

HBG1/HBG2

Target Synonyms

TNCY; HBG-T1; HBG1/HBG2

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

TF-1

Application

ELISA, WB, IF/ICC

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HBG1/HBG2 (NP_000175.1).	Target Species	Human
Immunogen Sequence	MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVD	Uniprot ID	P69892

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HBG1/HBG2 (NP_000175.1).

Target Species

Human

Immunogen Sequence

MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVD

Uniprot ID

P69892

Background Information

Uniprot Id

P69892
Target Species

Human
Target Name

HBG2
Target Full Name

Hemoglobin subunit gamma-2
Target Function

Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
Target Involvement

Cyanosis transient neonatal (TNCY)
Target Protein Families

Globin family
Target Tissue Specificity

Red blood cells.
Target Research Area

Cardiovascular
Target Synonyms

Abnormal hemoglobin; FLJ76540; G gamma globin; Gamma 2 globin; Gamma-2-globin; Hb F Ggamma; HBG 2; HBG2; HBG2_HUMAN; Hemoglobin gamma 2 chain; Hemoglobin gamma G; Hemoglobin gamma G chain; Hemoglobin gamma-2 chain; Hemoglobin gamma-G chain; Hemoglobin subunit gamma 2; Hemoglobin subunit gamma-2; Methemoglobin; OTTHUMP00000069638
Target Background

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Rabbit anti-Human HBG1/HBG2 Polyclonal Antibody

Specifications

Immunogen Information

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