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The antibody against Histone H1t was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 150-207 of human Histone H1t (NP_005314.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against Histone H1t was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 150-207 of human Histone H1t (NP_005314.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-07303A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Histone H1t |
| Target Synonyms | H1t; H1.6; H1FT; HIST1H1T; dJ221C16.2; Histone H1t | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse testis, Rat testis | Application | ELISA, WB, IHC-P |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 150-207 of human Histone H1t (NP_005314.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | NKRAKKPRATTPKTVRSGRKAKGAKGKQQQKSPVKARASKSKLTQHHEVNVRKATSKK | Uniprot ID | P22492 |
Uniprot Id
P22492
Target Species
Human
Target Name
H1-6
Target Full Name
Histone H1t
Target Function
Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration (Probable).
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Histone H1/H5 family
Target Tissue Specificity
Testis-specific.
Target Synonyms
H1 histone family; member T (testis specific); H1FT ; H1T ; H1T_HUMAN; Hist1h1t; Histone cluster 1; H1t ; Histone H1t; Testicular H1 histone
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