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The antibody against IKZF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 300-440 of human IKZF2 (NP_001072994.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against IKZF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 300-440 of human IKZF2 (NP_001072994.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02279A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IKZF2 |
| Target Synonyms | ANF1A2; HELIOS; ZNF1A2; ZNFN1A2; IKZF2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, K-562, Mouse thymus, Rat thymus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 300-440 of human IKZF2 (NP_001072994.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | TYLGAEALHPLMQHPPSTIAEVAPVISSAYSQVYHPNRIERPISRETADSHENNMDGPISLIRPKSRPQEREASPSNSCLDSTDSESSHDDHQSYQGHPALNPKRKQSPAYMKEDVKALDTTKAPKGSLKDIYKVFNGEGE | Uniprot ID | Q9UKS7 |
Uniprot Id
Q9UKS7
Target Species
Human
Target Name
IKZF2
Target Full Name
Zinc finger protein Helios
Target Function
Associates with Ikaros at centromeric heterochromatin.
Target Subcellular Location
Nucleus.
Target Protein Families
Ikaros C2H2-type zinc-finger protein family
Target Synonyms
ANF1A2; HELIOS; IKAROS family zinc finger 2; Ikaros family zinc finger protein 2; IKZF 2; IKZF2; IKZF2_HUMAN; MGC34330; Zinc finger DNA binding protein Helios; Zinc finger protein Helios; Zinc finger protein subfamily 1A 2; ZNF1A2
Target Background
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
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