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Rabbit anti-Human IKZF2 Polyclonal Antibody

The antibody against IKZF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 300-440 of human IKZF2 (NP_001072994.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02279A

The antibody against IKZF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 300-440 of human IKZF2 (NP_001072994.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-02279A ClonalityPolyclonal
Host SpeciesRabbitTarget NameIKZF2
Target SynonymsANF1A2; HELIOS; ZNF1A2; ZNFN1A2; IKZF2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, K-562, Mouse thymus, Rat thymusApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 300-440 of human IKZF2 (NP_001072994.1).Target SpeciesHuman
Immunogen SequenceTYLGAEALHPLMQHPPSTIAEVAPVISSAYSQVYHPNRIERPISRETADSHENNMDGPISLIRPKSRPQEREASPSNSCLDSTDSESSHDDHQSYQGHPALNPKRKQSPAYMKEDVKALDTTKAPKGSLKDIYKVFNGEGEUniprot IDQ9UKS7
Background Information
  • Uniprot Id

    Q9UKS7

  • Target Species

    Human

  • Target Name

    IKZF2

  • Target Full Name

    Zinc finger protein Helios

  • Target Function

    Associates with Ikaros at centromeric heterochromatin.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Ikaros C2H2-type zinc-finger protein family

  • Target Synonyms

    ANF1A2; HELIOS; IKAROS family zinc finger 2; Ikaros family zinc finger protein 2; IKZF 2; IKZF2; IKZF2_HUMAN; MGC34330; Zinc finger DNA binding protein Helios; Zinc finger protein Helios; Zinc finger protein subfamily 1A 2; ZNF1A2

  • Target Background

    This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

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