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The antibody against INTS5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human INTS5 (NP_085131.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against INTS5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human INTS5 (NP_085131.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-06136A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INTS5 |
| Target Synonyms | INT5; KIAA1698; INTS5 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HT-29, MCF7 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human INTS5 (NP_085131.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6P9B9 | Immunogen Sequence |
Uniprot Id
Q6P9B9
Target Species
Human
Target Name
INTS5
Target Full Name
Integrator complex subunit 5
Target Function
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
Target Subcellular Location
Nucleus membrane; Multi-pass membrane protein. Nucleus. Cytoplasm.
Target Protein Families
Integrator subunit 5 family
Target Synonyms
INTS5; KIAA1698; Integrator complex subunit 5; Int5
Target Background
The Integrator complex is a complex that associates with the C-terminal domain of RNA polymerase II large subunit. This complex is brought to U1 and U2 small nuclear RNA genes, where it is involved in the transcription and processing of their transcripts. The protein encoded by this gene represents a subunit of the Integrator complex.
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