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Rabbit anti-Human ITPKA Polyclonal Antibody

The antibody against ITPKA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 141-461 of human ITPKA (NP_002211.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06913A

The antibody against ITPKA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 141-461 of human ITPKA (NP_002211.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-06913A ClonalityPolyclonal
Host SpeciesRabbitTarget NameITPKA
Target SynonymsIP3KA; IP3-3KA; ITPKAFormLiquid
Species ReactivityMouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brain, Mouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 141-461 of human ITPKA (NP_002211.1).Target SpeciesHuman
Uniprot IDP23677Immunogen Sequence
Background Information
  • Uniprot Id

    P23677

  • Target Species

    Human

  • Target Name

    ITPKA

  • Target Full Name

    Inositol-trisphosphate 3-kinase A

  • Target Synonyms

    ITPKA; Inositol-trisphosphate 3-kinase A; EC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A

  • Target Background

    Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins(1, 3, 4, 5)P4. The activity of the inositol 1, 4, 5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.

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