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Rabbit anti-Human MLC1 Polyclonal Antibody

The antibody against MLC1 was raised in rabbit using the Human MLC1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-54604A

The antibody against MLC1 was raised in rabbit using the Human MLC1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$600.00

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Specifications


Cat.No ADC-54604A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMLC1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman MLC1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ15049
Background Information
  • Uniprot Id

    Q15049

  • Target Species

    Human

  • Target Name

    MLC1

  • Target Full Name

    Membrane protein MLC1

  • Target Function

    Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.

  • Target Involvement

    Leukoencephalopathy, megalencephalic, with subcortical cysts, 1 (MLC1)

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum.

  • Target Tissue Specificity

    Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus.

  • Target Synonyms

    KIAA0027; LVM; Megalencephalic leukoencephalopathy with subcortical cysts 1; Membrane protein MLC1; MLC; MLC1; MLC1_HUMAN; VL; WKL1

  • Target Background

    The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

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