Rabbit anti-Human MTBP Polyclonal Antibody

The antibody against MTBP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MTBP (NP_071328.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02328A

Number

Cat.No	ADA-02328A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MTBP
Target Synonyms	MDM2BP; MTBP	Form	Liquid
Species Reactivity	Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse spleen	Application	ELISA, WB

Cat.No

ADA-02328A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MTBP

Target Synonyms

MDM2BP; MTBP

Form

Liquid

Species Reactivity

Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse spleen

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MTBP (NP_071328.2).	Target Species	Human
Uniprot ID	Q96DY7	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MTBP (NP_071328.2).

Target Species

Human

Uniprot ID

Q96DY7

Immunogen Sequence

Background Information

Uniprot Id

Q96DY7
Target Species

Human
Target Name

MTBP
Target Full Name

Mdm2-binding protein
Target Function

Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
Target Protein Families

MTBP family
Target Synonyms

hMTBP; MDM 2 binding protein; MDM 2 BP; MDM2 (mouse double minute 2) binding protein 104kD; MDM2 (mouse double minute 2) binding protein; MDM2 binding protein; MDM2 BP; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein binding protein; Mdm2-binding protein; MDM2BP; Mouse double minute 2 homolog binding protein; MTBP; MTBP_HUMAN
Target Background

This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation.

Rabbit anti-Human MTBP Polyclonal Antibody

Specifications

Immunogen Information

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