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The antibody against MTMR4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 920-1195 of human MTMR4 (NP_004678.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against MTMR4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 920-1195 of human MTMR4 (NP_004678.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-05120A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MTMR4 |
| Target Synonyms | ZFYVE11; FYVE-DSP2; MTMR4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, HepG2, Mouse brain, Mouse liver | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 920-1195 of human MTMR4 (NP_004678.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NYA4 | Immunogen Sequence |
Uniprot Id
Q9NYA4
Target Species
Human
Target Name
MTMR4
Target Full Name
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4
Target Function
Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3).
Target Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein. Note=Localized to perinuclear region.
Target Protein Families
Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily
Target Tissue Specificity
Expressed in brain, heart, kidney, spleen, liver, colon, testis, muscle, placenta, thyroid gland, pancreas, ovary, prostate, skin, peripheral blood, and bone marrow.
Target Synonyms
FYVE domain containing dual specificity protein phosphatase 2; FYVE domain-containing dual specificity protein phosphatase 2; FYVE domain-containing dual specificity protein phosphatase FYVE DSP2; FYVE-DSP2; Mtmr4; MTMR4_HUMAN; Myotubularin related protein 4; Myotubularin-related protein 4; ZFYVE11 ; zinc finger FYVE domain containing 11; Zinc finger FYVE domain containing protein 11; Zinc finger FYVE domain-containing protein 11
Target Background
Enables protein phosphatase binding activity. Involved in regulation of phosphatidylinositol dephosphorylation. Located in endosome.
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