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Rabbit anti-Human NAGA Polyclonal Antibody

The antibody against NAGA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 312-411 of human NAGA (NP_000253.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-00858A

The antibody against NAGA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 312-411 of human NAGA (NP_000253.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-00858A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNAGA
Target SynonymsGALB; D22S674; NAGAFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, HL-60, Mouse liver, Mouse lung, Rat testisApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 312-411 of human NAGA (NP_000253.1).Target SpeciesHuman
Immunogen SequenceIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRTDMPYRYHSSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQUniprot IDP17050
Background Information
  • Uniprot Id

    P17050

  • Target Species

    Human

  • Target Name

    NAGA

  • Target Full Name

    Alpha-N-acetylgalactosaminidase

  • Target Function

    Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids.

  • Target Involvement

    Schindler disease (SCHIND); Kanzaki disease (KANZD)

  • Target Subcellular Location

    Lysosome.

  • Target Protein Families

    Glycosyl hydrolase 27 family

  • Target Synonyms

    NAGA; Alpha-N-acetylgalactosaminidase; EC 3.2.1.49; Alpha-galactosidase B

  • Target Background

    NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).

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